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Reduced urine albumin excretion in community based collaborative care in elderly Chinese with type 2 diabetes

Improved urine albumin excretion in community-based collaborative care in elderly Chinese with type 2 diabetes: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN19750520
Enrollment
260
Registered
2011-08-05
Start date
2004-04-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sustained type 2 diabetes management for the elderly Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

1. Twenty six patients randomized to intervention group were followed by each of the five multidisplinary diabetes care teams established in the four assigned communities 2. Each team included one pr

Sponsors

Ministry of Health of the People?s Republic of China (China)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Ages 60 and 80 years of age 2. Most recent HbA1c in the prior 6 months was more than or equal to 7.0% 3. Inhabitants in the respective community for more than or equal to 2 years 4. Participants with pubilic medical insurance 5. The proportion ratio is comparable in gender

Exclusion criteria

Exclusion criteria: 1. Patients with cancer 2. Patients with severe cirrhosis 3. Patients with malignant hypertension 4. Patients with severe concurrent illness that would substantially limit life expectancy or require extensive systemic treatment 5. Patients with cognitive, language or hearing impairment severe enough to preclude participation 6. Additionally, patients were also excluded if his or her family member was a physician or nurse

Design outcomes

Primary

MeasureTime frame
1. Changes in HbA1c level (target range <7.0%) 2. Changes in low density lipoprotein-cholesterol (LDL-C) concentration (target range <2.6mmol/L) 3. Changes in systolic and diastolic pressure (target range <130/80mmHg) 4. Change in urinary albumin excretion rate (UAER) (target range <30mg/d) 5. The HbA1c level was measured by a high-performance liquid chromatographic assay(Primus), with a normal reference range of 4.0% to 6.0% 6. Blood pressure was measured twice with a mercury sphygmomanometer in the right arm with the patient in a sitting position after a rest of 5 minutes 7. Serum LDL-C and urinary albumin concetration were determined by standard biochemical methods using a chemistry analyzer (Beckman Coulter Synchron clinical system DXC-800)

Secondary

MeasureTime frame
1. Measurement of: 1.1. Fasting plasma glucose (FPG) 1.2. Total cholesterol (TC) 1.3. Triglyceride (TG) 1.4. High density lipoprotein-cholesterol (HDL-C) 1.5. Depression screening by the Center for Epidemiologic Studies Depression Scale (CES-D) 2. Plasma glucose, TC, TG and HDL-C were determined by standard biochemical methods using a chemistry analyzer(Beckman Coulter Synchron clinical system DXC-800). 3. Depressive symptoms were evaluated by the CES-D scale which contains 20 items (range 0-60) where a score >16 is considered depressed

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026