Cancer Cancer
Conditions
Interventions
A prospective controlled clinical trial with intervention in the diet for six months in cancer patients from the Onkologikoa Foundation (single-centre) will be conducted. After diagnosis and prior to
Sponsors
AZTI
Onkologikoa Foundation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients of any type of Cancer who initiate a chemotherapy treatment, and who understand their participation in the trial. 2. Neoadjuvant, adjuvant and metastatic treatments will be considered. 3. A life expectancy of at least 1 year. 4. Age less than 70 years. 5. A body mass index (BMI) less than 35.
Exclusion criteria
Exclusion criteria: 1. Diabetic or with other risk factors related to lipid metabolism such as metabolic syndrome. 2. Allergy to fish. 3. Severe malnutrition, cachexia or anorexia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The lipid profile of the erythrocyte membrane is measured using GC-MS (Gas Chromatography Mass Spectrometry) in blood simples (1 ml) at baseline and the end of chemotherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quality of life is measured using validated EORTC questionnaires (QLQ-C30) and a specific module for different types of cancer (QLQ-BR23, QLQ-CR29, QLQ-OV28 and QLQ-PR25) at an intermediate point of the intervention treatment and at the end of the chemotherapy treatment. 2. Sensory alterations in taste, smell and appetite, and food preferences are measured using a questionnaire (defined in Amézaga J., et al., 2018) at baseline, at an intermediate point of the intervention treatment and at end of the chemotherapy treatment. 3. Nutritional habits are measured using a food frequency questionnaire (validated for the Spanish population in the PREDIMED study - Fernandez-Ballart, J.D., et al., 2010) at baseline and at the end of the chemotherapy treatment. | — |
Countries
Spain
Outcome results
None listed