How can we improve opioid assisted medical treatment for people with externalizing behavior?

Multicentre RCT comparing two interventions targeting externalizing behavior in patients enrolled in opioid agonist treatment (OAT)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN19554367

Enrollment

137

Registered

2020-09-04

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Externalising behavior Mental and Behavioural Disorders

Interventions

A parallel group, two arm, superiority trial comparing ILC with MOVE individual treatment for opioid use disorder (OUD). Participants will be recruited at four Danish treatment centers in four large

substance use

every day functioning

illegal activities, social interaction with individuals (family, friends, acquaintances) with non-criminal behavior and/or with no substance abuse

employment/educational activities. The two interventions that are tested in the trial: 1. The Impulsive Lifestyle program (ILC): Eight sessions targeting externalizing and criminal behavior. The ILC a

the Danish National Patient Register (Land

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Enrolment in opioid assisted treatment 2. Externalizing behavior assessed with EP6 (AdultMap) 3. Ability to engage in individual treatment sessions

Exclusion criteria

Exclusion criteria: 1. Current psychosis 2. Severe aggressive and chaotic behavior

Design outcomes

Primary

Measure	Time frame
1. Dropout from treatment as defined by being discharged for any reason other than having completed the treatment program	—

Secondary

Measure	Time frame
1. Use of substances other than prescribed medications. Substance use is measured in all attended sessions using TEM screening (Trivsels og Effekt Monitorering). TEM consists of 17 items of which eight are related to substance use and will be used to monitor potential substance use in the last seven days before each counseling session. Further, participants will be asked about substance use within the last month (AdultMap) 2. Everyday functioning (concentration, planning, keeping appointments, sleep, eating habits, cleaning etc.) last month (AdultMap) and last week (TEM screening in counselling session) 3. Illegal activities last month (AdultMap) 4. Social interaction with individuals (family, friends, acquaintances) with non-criminal behavior and/or with no substance abuse (AdultMap) in last month 5. Employment/educational activities (AdultMap) in last month	—

Measure

Time frame

1. Use of substances other than prescribed medications. Substance use is measured in all attended sessions using TEM screening (Trivsels og Effekt Monitorering). TEM consists of 17 items of which eight are related to substance use and will be used to monitor potential substance use in the last seven days before each counseling session. Further, participants will be asked about substance use within the last month (AdultMap) 2. Everyday functioning (concentration, planning, keeping appointments, sleep, eating habits, cleaning etc.) last month (AdultMap) and last week (TEM screening in counselling session) 3. Illegal activities last month (AdultMap) 4. Social interaction with individuals (family, friends, acquaintances) with non-criminal behavior and/or with no substance abuse (AdultMap) in last month 5. Employment/educational activities (AdultMap) in last month

—

Countries

Denmark

Contacts

Public ContactBirgitte Thylstrup

bt.crf@psy.au.dk+45 2158 7881

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 16, 2026