Single dose combination of sulfametoxazole/trimethoprim after percutaneous endoscopic gastrostomy

Single dose combination of sulfametoxazole/trimethoprim after percutaneous endoscopic gastrostomy versus standard prophylaxis before percutaneous endoscopic gastrostomy: a single centre double blind randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18677736

Enrollment

200

Registered

2010-01-04

Start date

2005-06-03

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Percutaneous endoscopic gastrostomy procedure Surgery Attention to artificial openings

Interventions

Single dose of 20 ml oral solution of sulfamethoxazole/trimethoprim (Bactrim®) given in the PEG-catheter immediately after PEG compared to standard treatment (single dose of 1.5 g of cefuroxime [Zinac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged greater than or equal to 15 years, either sex 2. Need for PEG 3. Gives oral consent to the study 4. No contraindication for PEG

Exclusion criteria

Exclusion criteria: 1. Ongoing antibiotic treatment 2. Allergy to study drug or standard treatment 3. Saying no to participation 4. Too sick to be able to give consent

Design outcomes

Primary

Measure	Time frame
Parastomal infection at follow up	—

Secondary

Measure	Time frame
Measured at baseline and follow up: 1. Highly sensitive C-reactive protein 2. White blood cell count 3. Body mass index (BMI) 4. Complications	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 31, 2026