Early detection and intervention of anorexia nervosa

Early detection and intervention of anorexia nervosa in adolescent girls: a randomized controlled trial comparing a family-oriented, internet-based intervention with a control group without intervention

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18614564

Enrollment

100

Registered

2012-03-12

Start date

2010-02-01

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa Mental and Behavioural Disorders Anorexia nervosa

Interventions

Randomized controlled trial comparing a 6-week intervention group to a monitored, non-intervention control group with outcome comparison at post-treatment and every 6 months E@T (Eltern als Therapeute

German version of P@N - Parents Act Now, Stanford Medical School). The intervention consists of an online program for parents of adolescent daughters with 6 sessions over 6 weeks mode

in- or outpatient treatment) if necessary. We favor an online program because such programs increase ease of dissemination, can be readily adapted and updated, provide contents 24 hour

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Female 2. Age 11 - 17 years 3. Informed consent by adolescent girl and their parents 4. Being at high risk for anorexia nervosa (AN), meaning to fulfill the combination AB or BC or ABC of the following variables: A. High weight and shape concerns B. Low weight (below 90% IBW) or normal weight (90-115% IBW) but weight loss of at least 5% in the past 6 months or >115% IBW but weight loss of at least 10% in the past 6 months C. Presence of at least one the following risk factors: High-level perfectionism, family history of ED, driven exercise (excessive engagement in physical activities) or primary or secondary amenorrhea

Exclusion criteria

Exclusion criteria: 1. Current full eating disorder diagnosis 2. Treatment for ED within the past six months 3. Acute suicidal ideation 4. Drug or alcohol abuse or dependence

Design outcomes

Primary

Measure	Time frame
AN symptoms: 1. Weight normalization - chnages in BMI 2. Weight and shape concerns, eating concerns, restraint (restricitive eating): Eating Disorder Examination (EDE, interview)	—

Secondary

Measure	Time frame
1. Risk status (as described in inclusion criteria, questionnaire) 2. Full or partial AN diagnoses: Eating Disorder Examination (EDE, interview) 3. Drive for thinness, body dissatisfaction: Eating Disorder Inventory 2 (EDI-2, questionnaire) 4. Self-esteem: Rosenberg Self-Esteem Scale (RSE, questionnaire) 5. Depression: Beck's Depression Inventory II (BDI-II, questionnaire) 6. Perfectionism: Frost Multidimensional Perfectionism Scale (MPS-F, questionnaire) 7. Social adjustment: Social Adjustment Scale (SAS, German version: Fragebogen zur sozialen Integration, FSI, questionnaire)	—

Measure

Time frame

1. Risk status (as described in inclusion criteria, questionnaire) 2. Full or partial AN diagnoses: Eating Disorder Examination (EDE, interview) 3. Drive for thinness, body dissatisfaction: Eating Disorder Inventory 2 (EDI-2, questionnaire) 4. Self-esteem: Rosenberg Self-Esteem Scale (RSE, questionnaire) 5. Depression: Beck's Depression Inventory II (BDI-II, questionnaire) 6. Perfectionism: Frost Multidimensional Perfectionism Scale (MPS-F, questionnaire) 7. Social adjustment: Social Adjustment Scale (SAS, German version: Fragebogen zur sozialen Integration, FSI, questionnaire)

—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 24, 2026