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A prospective randomised trial on the palatability and efficacy of Coca-Cola Zero® versus water for polyethylene glycol bowel preparation before colonoscopy

A prospective randomised trial on the palatability and efficacy of Coca-Cola Zero® versus water for polyethylene glycol bowel preparation before colonoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN18516614
Enrollment
200
Registered
2015-08-02
Start date
2013-12-04
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatability, safety, and efficacy of Coca-Cola Zero as a solvent for polyethylene bowel preparation for colonoscopy Digestive System

Interventions

All patients received two sachets of Fortrans (Beaufour Ipsen Pharma, Paris, France), each containing 64 g macrogol 4000, 5.7 g sodium sulphate, 1.68 g sodium bicarbonate, 1.46 g sodium chloride, 0.75

Sponsors

Seow-Choen Colorectal Centre Pte Ltd (Singapore)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adults over 21 years old 2. Healthy or with mild or well controlled chronic illnesses. Control of systemic disease was determined on the basis of no increase in medication or development of new symptoms or complications within the past year 3. Scheduled for an elective colonoscopy at our institution

Exclusion criteria

Exclusion criteria: 1. Pregnant patients 2. Patients with suspected intestinal obstruction 3. Patients at risk of aspiration 4. Patients with serious systemic or poorly controlled chronic illnesses

Design outcomes

Primary

MeasureTime frame
The palatability of the PEG+Coke solution compared to the PEG+water solution. Palatability was judged based on a four-point questionnaire which was issued to the patient prior to discharge.

Secondary

MeasureTime frame
1. Cleanliness of the bowel preparation was judged by the endoscopist as well as two endoscopy nurses during the colonoscopy 2. Adverse reactions, willingness to repeat the same solution again or recommend it to a friend were measured based on the same patient questionnaire prior to discharge after the endoscopy

Countries

Singapore

Contacts

Public ContactIsaac Seow-En

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026