Decrease dandruff and improve scalp health Skin and Connective Tissue Diseases
Conditions
Interventions
This is a single-center, double-blind, randomized, mix genders study. Subjects will remain in the study for about 7 weeks, including a 2-week run-in phase, 1-week balancing, and a 4-week test phase. T
Sponsors
Unilever (China)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. External subjects (not employees from Unilever or S.P.R.I.M. or Recruiting agency) 2. Aged between 18 and 60 years (inclusive) 3. Dandruff scalp condition (both sides half head total weighted head score AF equivalent =32 with grade C, difference between two sides <12) at screen v1 and rescreen v2 4. Subject’s scalp is free from cuts and abrasions 5. Understand the test procedure and agree to adhere to study requirements 6. Hair wash frequency =twice per week
Exclusion criteria
Exclusion criteria: 1. Currently pregnant, trying to be pregnant or breastfeeding (female only) 2. Have a history of serious illness that may require regular systemic medication (e.g. cancer, thyroid dysfunction, liver dysfunction) which may influence the study outcome (at the discretion of the Study Doctor). Subjects with stable thyroid conditions (medication / dosage has not changed within 12 months of the start of the study) may be included at the discretion of the Study Doctor 3. Current or frequent systemic treatment by a doctor for any active skin condition, on any body site 4. Sufferers of eczema of any area of the head or neck (during adult life) 5. Seborrhoeic dermatitis on the head or neck or severe dandruff, currently or within last 6 months 6. Diagnosed with psoriasis and have active lesions within last 2 years 7. Use of systemic anti-inflammatory medication on a frequent basis (at the discretion of the Study Doctor) Use of topical steroids on the scalp currently or within last 6 months 8. Recent or current regular use of systemic or inhaled steroids 9. Regular use of any other medication / topical products which might affect the outcome of the study (at the discretion of the Study Doctor) 10. Hair dyed/permed or chemically treated within 2 weeks of the run-in period 11. Have head lice or ringworm at any point in the study • Have any known allergies or sensitivities to ingredients in study products 12. Hair loss greater than Hamilton grade 3 for male or Ludwig grade 1 for female 13. Use of ketoconazole-based shampoo (e.g. Nizoral, Neutrogena Long-lasting) within last 6 months or Selenium sulfide-based shampoo (e.g. Selsun, L’Oreal Intensive Anti-Dandruff, Head and Shoulders intensive) within the last 3 months 14. Use of anti-dandruff shampoo or other anti-dandruff hair/scalp care products within the last 2 months 15. Concurrent participation in another scalp clinical study 16. Use of any medicine which in the opinion of the Study Doctor may affect the outcome of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scalp visual assessment by a trained assessor at baseline, and once per week from week 1- week 4. | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events will be measured and recorded throughout the study (4 weeks) | — |
Countries
China
Contacts
Public ContactYuanpei Li
Outcome results
None listed