Acute childhood diarrhea Signs and Symptoms
Conditions
Interventions
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Sponsors
Infinitus (China) Company Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants and children with an episode of mild to moderate acute diarrhea (>4 (semi)watery stools/day according to Bristol criteria (Bristol criteria =6)) lasting more than 12 h and less than 72 h, requiring hospitalization
Exclusion criteria
Exclusion criteria: 1. Subjects with clinical features of hypovolemic shock and/or necessitating admission at the intensive care unit 2. Taking immunosuppressive therapy 3. Known immunodeficiency disorder 4. Pancreatic dysfunction 5. Bloody diarrhea 6. Chronic gastrointestinal disease 7. Short bowel syndrome 8. Bilious or bloody vomitus 9. Probiotics 1 month before admission 10. Severe malnutrition
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Number of loose stools per day during the entire episode, measured using an appropriate CRF every day during the intervention | — |
Primary
| Measure | Time frame |
|---|---|
| Duration of diarrhea [time in hours from enrolment to the last abnormal (loose or liquid) stool], measured using an appropriate CRF every day during the intervention | — |
Countries
China
Outcome results
None listed