Cancer and deprescribing antithrombotic therapy at end-of-life Not Applicable
Conditions
Interventions
Intervention
A qualitative study design to gain insight and a deeper understanding of patients’ and clinicians’ experiences and perceptions of continuing and deprescribing antithrombotic therapy. This
Sponsors
Cardiff University
Aalborg University Hospital
Hospital Clínic de Barcelona
Assistance Publique – Hôpitaux de Paris
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients: 1. Aged 18 years old and over 2. Advanced cancer (whose life expectancy is less than one year, according to the healthcare professional identifying eligible participants) 3. Receiving antithrombotic medicine for one of the following diseases: atrial fibrillation/stroke prevention, mechanical heart valve, peripheral vascular disease, and deep vein thrombosis or pulmonary embolus 4. Capacity to give informed consent 5. Capacity to undertake an interview in English Companions: 1. Companions are defined as person(s) who look after and/or support the patient as identified and chosen by the patient to take part alongside them, should the companion wish to do so 2. Aged 18 years old and over 3. Capacity to give informed consent 4. Capacity to undertake an interview in English Clinicians: Clinicians practising in their chosen speciality for 10 years or more, from across the following specialities: oncology, care of the elderly, frailty, stroke medicine, palliative/hospice care, family physician/general practice, cardiology, respiratory medicine, and vascular surgery
Exclusion criteria
Exclusion criteria: Patients and companions: 1. Cognitive impairment 2. Unable to speak or understand English 3. Considered too unwell to participate in a 30-60 minute interview
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome variables are measured using a 30-60 minute interview at one time point: 1. Cancer patients’ (and companions’ if present) experiences, values, and perspectives on antithrombotic therapy measured using a semi-structured interview guide 2. Clinicians’ experiences of the current practice of continuing and deprescribing antithrombotic therapy to cancer patients, and their perceptions of key facilitators and barriers to deprescribing measured using a semi-structured interview guide | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
Denmark, France, Spain, United Kingdom, Wales
Contacts
Public ContactAnnmarie Nelson
Outcome results
None listed