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The effect of anxiety before surgery on recovery from anesthesia

The midbrain ventral tegmental area is essential for delayed awakening from general anesthesia of anxiety state: in vivo and in vitro

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN18373253
Enrollment
82
Registered
2020-11-18
Start date
2019-08-01
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with varicose great saphenous vein who received general anesthesia and elective surgery Surgery

Interventions

The participants are interviewed when they come to the anesthesia clinic for preoperative examination under the instruction of an anesthesiologist. The participants are asked to sit on a chair and ans

Sponsors

Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 18-65-year-old patients with varicose great saphenous vein who received general anesthesia and elective surgery

Exclusion criteria

Exclusion criteria: 1. Psychiatric disorders 2. Alzheimer's disease 3. Mental retardation 4. Cardiopulmonary severe dysfunction 5. Liver and kidney dysfunction 6. History of drug or alcohol abuse 7. ASA III-IV patients

Design outcomes

Primary

MeasureTime frame
Extubation time, defined as the time between drug withdrawal and the time at which a BIS greater than or equal to 85 was achieved and the tube could be removed

Secondary

MeasureTime frame
1. Post-anesthesia anesthesia recovery measured using Alderte score every 15 min in the post-anesthesia recovery room (PACU) 2. Postoperative pain visual analog scale (VAS) scores at 6 h, 12 h, and 24 h 3. Postoperative nausea and vomiting VAS scores at 6 h, 12 h, and 24 h 4. Postoperative restlessness measured using sedative and agitation scale (SAS) at 5, 10, 15 and 20 min after entering the PACU 5. Chills measured using postoperative shiver score at 5, 10, 15 and 20 min after entering the PACU 6. Operation length, measured as the time interval from the initiation to the end of surgery 7. Anesthesia length, measured as the time interval from the initiation of anesthesia to the end of surgery 8. Length of hospital stay, measured as discharge date minus admission day plus one

Countries

China

Contacts

Public ContactHui Wang
huihuismile@126.com+86 (0)18321806626

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026