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Dental remineralization with a silver nanoparticle compound

Effectiveness of remineralization with compound silver nanoparticles and fluoride varnish in caries lesions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN18357873
Enrollment
40
Registered
2024-08-19
Start date
2022-08-26
Completion date
Unknown
Last updated
2024-09-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries Oral Health

Interventions

Primary molars were distributed into two groups: Group A was treated with a compound based on silver nanoparticles and Group B with silver diamine fluoride compound as control treatment. Laser fluores

Sponsors

Universidad Nacional Autónoma de México
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children with caries lesions 2. Children agree to participate in the study

Exclusion criteria

Exclusion criteria: 1. Children with general disease 2. Molars with non-reversible pulpitis, abscesses

Design outcomes

Primary

MeasureTime frame
Remineralization measured for each caries lesion using the Diagnodent pen test (laser fluorescence) and data will be recorded at baseline and after each application: 15 days, 6 and 12 months

Secondary

MeasureTime frame
The arrest of caries lesions measured by considering the texture and colour of the caries lesions by clinical inspection with the aid of a WHO probe to classify them as active or arrested lesions at baseline and 12 months

Countries

Mexico

Contacts

Public ContactMaria Lilia Adriana Juarez Lopez
lilia.juarez@zaragoza.unam.mx+52 (0)5554342362

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026