Can vitamin supplements help school children in healing gum diseases?

Effectiveness of Vitamin C and Vitamin D supplements in the treatment of periodontal diseases in school-going children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18356310

Enrollment

306

Registered

2025-08-05

Start date

2021-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease Oral Health

Interventions

Cross-sectional phase 1 for baseline assessment followed by interventional phase 2 with modified RCT protocol among two groups (Group A with non-deficient children and group B with deficient children)

Eligibility

Sex/Gender

All

Age

4 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. School-going children 2. No systemic diseases 3. Not taking antibiotic therapy 4. 4-12 years of age

Exclusion criteria

Exclusion criteria: 1. Participants with systemic disease like diabetes or otherwise immunocompromised 2. Participants taking antibiotics

Design outcomes

Primary

Measure	Time frame
Gingival health measured using the Silness-Loe Gingival Index (GI) at baseline, 4 and 8 weeks	—

Secondary

Measure	Time frame
Probing depth measured using a Williams probe on a periodontal chart at baseline, 4 and 8 weeks	—

Countries

Pakistan

Contacts

Public ContactArooj Ul Hassan

arooj.ulhassan@ucd.uol.edu.pk+92 (0)3444420953

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 3, 2026