Occupational health and safety among health care personnel in a COVID-19 pandemic

Predictive value of biological, physiological and analytical biomarkers with the use of personal protection equipment in COVID-19: observational, prospective, analytical, intervention and multicenter study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN18348009

Enrollment

Registered

2020-04-15

Start date

2020-04-16

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications or secondary effects derived from the use of personal protective equipment against biological risks Not Applicable

Interventions

Volunteers (workers in a COVID19 treatment unit) undergo a structured and objective evaluation. Physiological variables (respiratory rate, saturation, heart rate, systolic and diastolic blood pressure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Workers (doctors, nurses and assistants) in the COVID19 treatment unit with the biological risks training course 2. Aged over 18 years 3. Provide informed consent

Exclusion criteria

Exclusion criteria: 1. Pregnant 2. Psychiatric pathology 3. Do not sign the informed consent 4. Not to be part of the HURH and Covid-Fair staff during the month of April

Design outcomes

Primary

Measure	Time frame
1. Respiratory rate, assessed by clinical observation at baseline and at the end of the 4-hour workday 2. Oxygen saturation, assessed using a Physio LifePAK® 15 monitor at baseline and at the end of the 4-hour workday 3. Heart rate, assessed using a Physio LifePAK® 15 monitor at baseline and at the end of the 4-hour workday 4. Blood pressure, assessed using a Physio LifePAK® 15 monitor at the start of the study and at the end of the 4-hour workday 5. Tympanic temperature evaluated using a Braun ThermoScan® PRO 6000 model at baseline and at the end of the 4-hour workday 6. Weight, with the TANITA BC 545-N scale at baseline 8. Size, with the SECA 206 tape measure at baseline 9. Analytical biomarkers: pH, pCO2, pO2, cHCO3-, BE (ecf), cSO2, Na +, K +, Ca ++, Cl-, TCO2, Agap, AGapK, Hct, Hb, BE (b), Glu , Lac, BUN, Urea and Crea, evaluated using COPD Siemens Healthcare at baseline and at the end of the 4-hour workday 10. Medical history of interest, through a structured questionnaire at baseline 11. Level of physical activity using the IPAQ questionnaire at baseline	—

Measure

Time frame

1. Respiratory rate, assessed by clinical observation at baseline and at the end of the 4-hour workday 2. Oxygen saturation, assessed using a Physio LifePAK® 15 monitor at baseline and at the end of the 4-hour workday 3. Heart rate, assessed using a Physio LifePAK® 15 monitor at baseline and at the end of the 4-hour workday 4. Blood pressure, assessed using a Physio LifePAK® 15 monitor at the start of the study and at the end of the 4-hour workday 5. Tympanic temperature evaluated using a Braun ThermoScan® PRO 6000 model at baseline and at the end of the 4-hour workday 6. Weight, with the TANITA BC 545-N scale at baseline 8. Size, with the SECA 206 tape measure at baseline 9. Analytical biomarkers: pH, pCO2, pO2, cHCO3-, BE (ecf), cSO2, Na +, K +, Ca ++, Cl-, TCO2, Agap, AGapK, Hct, Hb, BE (b), Glu , Lac, BUN, Urea and Crea, evaluated using COPD Siemens Healthcare at baseline and at the end of the 4-hour workday 10. Medical history of interest, through a structured questionnaire at baseline 11. Level of physical activity using the IPAQ questionnaire at baseline

—

Secondary

Measure	Time frame
1. Headache presence measured using self-report at the end of the 4 hours of working with the equipment 2. Presence of serious adverse events during the use of protective equipment measured using self-report at the end of the 4 hours of working with the equipment 3. Presence of chafing, wounds, etc., due to the use of protective equipment measured using self-report at the end of the 4 hours of working with the equipment 4. Perception of the state of physical fatigue at the end of the working day with the protective equipment measured using self-report at the end of the 4 hours of working with the equipment 5. Time in COVID19 zone measured using self-report at the end of the 4 hours of working with the equipment	—

Measure

Time frame

1. Headache presence measured using self-report at the end of the 4 hours of working with the equipment 2. Presence of serious adverse events during the use of protective equipment measured using self-report at the end of the 4 hours of working with the equipment 3. Presence of chafing, wounds, etc., due to the use of protective equipment measured using self-report at the end of the 4 hours of working with the equipment 4. Perception of the state of physical fatigue at the end of the working day with the protective equipment measured using self-report at the end of the 4 hours of working with the equipment 5. Time in COVID19 zone measured using self-report at the end of the 4 hours of working with the equipment

—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026