Obsessive Compulsive Disorder (OCD) - Predominantly Obsessive type Mental and Behavioural Disorders
Conditions
Interventions
70 patients with a diagnosis of predominantly obsessional OCD were recruited from inpatient or outpatient departments of NIMHANS. They were randomly allocated into two groups – Mindfulness Integrated
Sponsors
National Institute of Mental Health and Neurosciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with a primary diagnosis of OCD - predominantly obsessions as per DSM 5 criteria 2. Few or no overt compulsions 3. Y-BOCS score at baseline 10 or more 4. CGI – severity criteria – moderately ill 5. Aged between 18 and 55 years 6. Minimum education of class X 7. Patients fluent in Bengali, English or Hindi with ability to comprehend English text in assessment tools 8. Patients who are either drug-naïve, drug-free or stabilized on medication for 2 months prior to the entry to the study
Exclusion criteria
Exclusion criteria: 1. Motor compulsions which cause significant distress or significantly interferes with daily functioning 2. History of head injury, neurological illness or history suggestive of organicity 3. Primary diagnosis of schizophrenia and any other psychosis, current psychoactive substance dependence except nicotine dependence, or mental retardation 4. Patients who had received any adequate trial of cognitive behavior therapy or any other structured psychotherapy in the previous year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Severity, avoidance and insight of obsessive compulsive symptoms assessed using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) at baseline, post-intervention and 3 months follow-up 2. Severity of overall illness assessed using the Clinical Global Impression Scale (CGI) at baseline, post-intervention and 3 months follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Depression, anxiety and stress assessed using the Depression Anxiety Stress Scale (DASS-21) at baseline, post-intervention and 3 months follow-up 2. Dysfunctional beliefs assessed using the Obsessive Belief Questionnaire (OBQ-21) at baseline, post-intervention and 3 months follow-up 3. Mindfulness skills assessed using the Five facet Mindfulness Questionnaire (FFMQ) at baseline, post-intervention and 3 months follow-up 4. Experiential avoidance assessed using the Acceptance and Action Questionnaire (AAQ-II) at baseline, post-intervention and 3 months follow-up 5. Overall quality of life assessed using the World Health Organization Quality of Life (WHOQOL-BREF) questionnaire at baseline, post-intervention and 3 months follow-up 6. Social and functional impairment assessed using the Work and Social Adjustment Scale (WSAS) at baseline, post-intervention and 3 months follow-up 7. Degree and quality of homework assessed using the Homework Compliance Scale at post intervention and 3-months follow-up | — |
Countries
India
Outcome results
None listed