Knee osteoarthritis Musculoskeletal Diseases
Conditions
Interventions
Single-centre trial in which we plan to investigate the biomechanical effects of different footwear. This will be achieved with a laboratory cross-over study at the University of Salford, during which
Sponsors
University of Salford (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age range 40-85 (upper age limit due to the amount of walking involved in the study) 2. Ability to stand and walk independently 3. Speak and understand written English 4. Ability to walk without any walk assistive for at least 250 m 5. Clinical diagnosis of knee OA according to American College of Rheumatology (ACR) (Altman et al. 1986) (if they are a participant with knee OA) 6. Pain for at least 6 months' duration (if they are a participant with knee OA) 7. Pain or difficulty in rising from sitting and/or climbing stairs (if they are a participant with knee OA)
Exclusion criteria
Exclusion criteria: 1. Complex pain conditions such as diabetic neuropathic pain, fibromyalgia 2. Have had previous surgery to the lower limb 3. BMI >33 since it is not possible to perform accurate measurements on individuals with excess adipose tissue 4. Lower limb arthroplasty 5. Any systemic inflammatory disorders, such as rheumatoid arthritis 6. Any balance disorders which may increase the risk of a fall
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscular co-contraction of the quadriceps and hamstrings and the quadriceps and gastrocnemius, derived from electromyography (EMG) data collected from the specified muscles during walking | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The knee extensor moment outcome calculated from force and kinematic (3D motion) data collected during walking 2. The centre of mass position derived from full-body 3D motion data during walking | — |
Countries
England, United Kingdom
Outcome results
None listed