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Discontinuation of hormone replacement therapy: TAPER study

DisconTinuAtion of hormone rePlacement thERapy (TAPER study); How and why do women decide and experience stopping HRT, why do women decide to restart?

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN18292146
Enrollment
115
Registered
2026-02-02
Start date
2025-08-19
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Use of Hormone Replacement Therapy Nutritional, Metabolic, Endocrine

Interventions

Project Plan At the outset, I will establish three groups: PPI Panel consisting of women (with experience of stopping HRT) from diverse backgrounds. Project Research Group (PRG) consisting of wo

Sponsors

University of Birmingham
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 99 Years

Inclusion criteria

Inclusion criteria: Women: 1. Aged over 45 years 2. Recent experience of discontinuing or attempting to discontinue HRT (in the last 3 years) For HCPs: 1. Working in NHS and delivering menopause care

Exclusion criteria

Exclusion criteria: For women: Severe mental health or learning difficulties meaning they cannot give informed consent. This will be at the discretion of the GP screening for potential participants or the researcher taking informed consent

Design outcomes

Primary

MeasureTime frame
WP1. Experiences of women discontinuing HRT and their experiences of re-starting HRT, through qualitative interviews. WP1 also uses qualitative interviews to explore the experiences of HCP when they advise women to discontinue HRT. Data will be analysed using framework analysis WP2. Successfully stopping HRT measured using patient records at the end of the study

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

England, United Kingdom

Contacts

Public ContactEleanor;Sarah Molloy;Hillman

;

e.molloy@bham.ac.uk;s.c.hillman@bham.ac.uk-;-

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026