A randomised controlled trial investigating the role of subfascial endoscopic perforator vein surgery (SEPS) in the prevention of recurrence in primary long saphenous varicose veins

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18288048

Enrollment

Registered

2003-09-12

Start date

2000-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Primary long saphenous varicose veins Circulatory System Varicose veins of lower extremities

Interventions

Randomised controlled trial randomised into two groups: Group 1 - subfascial endoscopic perforator vein surgery (SEPS) Group 2 - standard open procedure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Venous reflux (greater than 0.5 s) of the greater saphenous vein (GSV) 2. Additional incompetent perforating veins (IPVs)

Exclusion criteria

Exclusion criteria: 1. Ulceration, 2. Recurrent veins 3. Deep venous reflux/thrombosis 4. Saphenopopliteal reflux

Design outcomes

Primary

Measure	Time frame
1. Improvement in function measured by refill time, 2. Incidence of recurrent reflux 3. Clinical recurrence 4. Cosmetic results	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 7, 2026