Dynamically monitor diaphragmatic function in mechanically ventilated patients in the intensive care unit (ICU) using point-of-care ultrasound, explore its trajectory, and evaluate its predictive value for weaning outcomes. Respiratory
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old 2. Intubated orally or nasotracheal with invasive mechanical ventilation 3. Expected duration of mechanical ventilation > 48 hours 4. Informed consent was obtained from their legal representatives of patients
Exclusion criteria
Exclusion criteria: 1. Previous known diaphragmatic disease or paralysis (e.g., cervical spinal cord injury, amyotrophic lateral sclerosis, etc.) 2. Previous history of thoracic surgery, especially involving the diaphragm or lung resection, may severely affect diaphragmatic anatomy 3. Use of neuromuscular blocking agents 4. History of chronic obstructive pulmonary disease 5. Pregnant women 6. Technical difficulties in surface ultrasound examination (e.g., severe subcutaneous emphysema, extreme obesity) 7. Other conditions considered by the investigator to be inappropriate for inclusion (e.g., terminal state, treatment withdrawal).
Countries
China