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Kinetics of left ventricular strains and untwist during the transitions from rest to exercise

Kinetics of left ventricular function and regional mechanics at the onset of exercise in sedentary and endurance-trained subjects

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN18219450
Enrollment
50
Registered
2018-03-23
Start date
2015-09-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac evaluations at rest and during effort in healthy young controls and endurance-trained cyclists Circulatory System

Interventions

This study was a pilot study to check the feasibility of fast evaluation of echocardiography every 15 seconds during exercise. Young male cyclists (18 – 25 years) and age-matched sedentary controls pe

Sponsors

University of Avignon
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Cyclists training at least 10 hours per week for at least 8 years or sedentary young men reporting regular training habits 2. 18-35 years old 3. Non-smokers 4. No history of diabetes, hypertension or cardiovascular disease 5. Normal clinical examination 6. In sinus rhythm 7. Screening echocardiography showing normal left and right heart morphology and function and the absence of valvular disease

Exclusion criteria

Exclusion criteria: 1. Smokers 2. History of diabetes, hypertension or cardiovascular disease 3. Abnormal sinus rhythm 4. Screening echocardiography shows abnormal left and right heart morphology and function and or valvular disease

Design outcomes

Primary

MeasureTime frame
Left ventricular strains and twist/untwist kinetics during the transitions from rest to exercise, measured non-invasively using 2D-strain echocardiography. Each subject of the study was evaluated one time only (i.e. transversal design)

Secondary

MeasureTime frame
Global systolic and diastolic functions, measured non-invasively using Doppler echocardiography. Each subject of the study was evaluated one time only (i.e. transversal design)

Countries

France

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026