Topic: Skin
Conditions
Interventions
76 participants will be randomised to two groups:
Group 1 will receive narrow band UVB phototherapy to the hands. Hands will be exposed to UVB light.
Group 2 will receive PUVA phototherapy to the ha
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patient has provided written informed consent for participation in the study prior to any study specific procedures 2. Palmar eczema not responding to topical treatments 3. Over 18 years of age 4. No topical treatments (except emollients for 48 hours) 5. No systemic treatments for eczema treatment for 3 months 6. Absence of clinical evidence of bacterial, fungal or viral infection 7. Not pregnant 8. Target Gender: Male & Female
Exclusion criteria
Exclusion criteria: 1. Inability to give informed consent 2. Significant eczema on the dorsal surface of the hands 3. Previous phototherapy within the last 3 months 4. Previous sunbed use within the last 3 months 5. Current involvement in other investigational studies or trials, or involvement within 3 months prior to study entry
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients responding (clear or almost clear PGA score) Timepoint(s): 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The percentage improvement in the Modified Total Lesion Symptom Score (mTLSS) 2. Dermatology Life Quality Index (DLQI)) 3. Health economic evaluation | — |
Countries
United Kingdom
Outcome results
None listed