Preventing preterm birth in Chinese women with a short cervix in singleton pregnancies

Cerclage pessary for preventing preterm birth in Chinese women with a short cervix in singleton pregnancies: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18185477

Enrollment

4000

Registered

2012-04-16

Start date

2008-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical insufficiency Pregnancy and Childbirth Incompetence of cervix uteri

Interventions

Women invited to participate were randomized into two arms: control group or pessary group. Randomization was performed using a computer-generated sequence and the allocation results were concealed in

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women with singleton viable pregnancy undergoing routine morphology ultrasonography at 18 ? 24 weeks found to have a cervix less than 25 mm

Exclusion criteria

Exclusion criteria: 1. Multiple pregnancies 2. Major fetal abnormalities defined as those that are lethal or require prenatal or postnatal surgery 3. Severe intra-uterine growth restriction (IUGR) 4. Cervical dilatation, painful uterine contractions, history of ruptured membranes, or prophylactic surgical cerclage before randomization 5. Patients who are unconscious, severely ill, mentally handicapped or under the age of 16 years

Design outcomes

Primary

Measure	Time frame
Preterm rate before 34 weeks	—

Secondary

Measure	Time frame
Perinatal morbidities and mortality	—

Countries

Hong Kong

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026