Effects of gene expression pattern and RAS/BRAF mutations on the course of colorectal cancer

The gene expression pattern and RAS/BRAF mutation status of tumor as a prognostic factor for colorectal cancer

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18093312

Enrollment

300

Registered

2015-10-20

Start date

2015-11-01

Completion date

Unknown

Last updated

2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer Cancer Colorectal cancer

Interventions

Tumors of operated patients will be assessed for expression profile and somatic KRAS/BRAF mutations. All cases will be then assigned to one of five different subtypes, as described Sadanandam and co

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Potentially curable colorectal cancer

Exclusion criteria

Exclusion criteria: 1. Participants that have had preoperative chemotherapy and/or radiotherapy 2. Patient that refuse to follow the study protocol

Design outcomes

Primary

Measure	Time frame
Disease-free survival (DFS)	—

Secondary

Measure	Time frame
1. Overall survival (OS) 2. Time to relapse (TTR)	—

Countries

Russian Federation

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026