Deep vein thrombosis Circulatory System Deep vein thrombosis
Conditions
Interventions
Participants are randomized to one of two groups (foot pump or without foot pump). Randomization is performed on the day before the operation using sealed envelopes containing a slip indicating the al
Sponsors
Japanese National Hospital Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 20 and over 2. Undergoing knee replacement surgery for primary joint disease, including osteoarthritis (OA) and rheumatoid arthritis (RA)
Exclusion criteria
Exclusion criteria: 1. Presence of predefined risk factors for bleeding, coagulation disorders, heart failure (New York Heart Association class III or IV), significant renal dysfunction (creatinine clearance <30?mL/min) 2. Abnormalities in biochemical measurements (aspartate aminotransferase or alanine aminotransferase =5 times the upper limit of normal or total bilirubin =2 times the upper limit of normal) 3. Those scheduled to undergo bilateral joint replacement or reoperation 4. Unable to walk 5. Uncontrolled cardiovascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Symptomatic DVT rate is detected by ultrasonography at baseline and 10 days postoperative 2. Non-symptomatic DVT rate is detected by ultrasonography at baseline and 10 days postoperative 3. Fatal/nonfatal pulmonary embolism (PE) rate is detected by computed tomography at baseline and 28 days postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
Japan
Contacts
Public ContactSatoru Motokawa
Outcome results
None listed