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Arm cycle ergometry in the ICU rehabilitation pilot study

Arm cycle ergometry in the ICU (ACE-ICU) rehabilitation pilot: a pilot randomized controlled trial of arm cycle ergometry versus routine rehabilitation in mechanically ventilated patients

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN18074484
Enrollment
60
Registered
2025-12-31
Start date
2026-04-15
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated ICU patients who independently used their arms for functional activities (e.g., eating, dressing) before their critical illness. Injury, Occupational Diseases, Poisoning

Interventions

Usual ICU and Ward rehabilitation – Patients will receive routine rehabilitation (e.g., interventions from physiotherapists and occupational therapists) per current institutional practice. Routine ph

Sponsors

McMaster University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adults (>= 18 years old) 2. Who used their upper limbs for functional activities (e.g., dressing, bathing) before their critical illness 3. Within the first 7 days of their ICU stay 4. Received or are receiving mechanical ventilation (invasive or non-invasive) for >24 hours 5. Within the first 4 days of starting mechanical ventilation

Exclusion criteria

Exclusion criteria: 1. Known shoulder pathology 2. Impaired shoulder range of motion 3. Any condition impairing patients’ ability to cycle (e.g., arm fracture) 4. Proven or suspected neuromuscular weakness affecting the arms 5. Unable to follow commands pre-critical illness 6. Expected hospital mortality >90% 7. Body habitus unable to fit the bike, palliative goals of care 8. Persistent therapy exemptions in the first 4 days of ICU stay (e.g., cardiorespiratory instability, active major bleeding)

Countries

Australia, Canada

Contacts

Public ContactMichelle Kho
khome@mcmaster.ca+1 2892370194

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026