Time variability of flush-onset and flush tolerabililty in individuals given 500 mg niacin (nicotinic acid): a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18054903

Enrollment

Registered

2002-11-14

Start date

2002-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous reactions (flushing) Skin and Connective Tissue Diseases Cutaneous reactions

Interventions

Participants divided into two groups: 1. Verum group takes one 500 mg tablet of niacin 2. The control group takes a placebo

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age range 20 - 60 years 2. Currently enrolled at The Canadian College of Naturopathic Medicine (CCNM) 3. Not currently taking any prescribed medication that influences gastric acid secretion 4. Does not have current or past liver disease (e.g., chronic active hepatitis, cirrhosis, etc) 5. Does not have current or past history of gout or active gout 6. Does not have current or past gastrointestinal disease (e.g., peptic ulcer disease, gastric cancer, etc) 7. Does not have current or past diagnosis of diabetes mellitus 8. Does not have a past episode or history of intolerance to niacin 9. Was able to complete the intake form

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 18, 2026