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Psychological determiners of distincts fatigue trajectories in colorectal patients undergoing chemotherapy

Psychological determiners of distincts fatigue trajectories in colorectal patients undergoing chemotherapy: a latent class analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN18044948
Enrollment
200
Registered
2018-12-27
Start date
2015-10-01
Completion date
Unknown
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metastatic colorectal cancer Cancer Colorectal cancer

Interventions

Participants meet a psychologist-researcher at T0 and indicate their level of fatigue on a visual analog scale (VAS) every two weeks during 6 months. They also fill in questionnaires for psychological

Sponsors

National Cancer Institute
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age >18 years 2. Colorectal cancer with metastasis 3. Chemotherapy intravenous (d1-d14) for at least 2 months

Exclusion criteria

Exclusion criteria: 1. Younger than 18 years 2. Not able to understand french and those with cognitive impairment 3. Psychiatric disorder

Design outcomes

Primary

MeasureTime frame
1. Fatigue is assessed using the Daily Cancer Fatigue Scale (DFCS), a VAS with two single items questions: "I lack energy" and "I feel weary" to assess both physical and psychological Cancer Related Fatigue at baseline and every two weeks for 6 months.

Secondary

MeasureTime frame
1. Fatigue measured using the Multidimensional Fatigue Inventory MFI (validated by Gentile et al., 2003) 2. Anxiety and Depression is measured using the Hospital Anxiety and Depression Scale HADS (developed by Zigmond and Snaith, 1983) 3. Coping strategy is measured using the Ways of Coping Checklist WCC-21 (validated by Cousson-Gélie et al., 2010) 4. Perceived control is assessed using the Cancer Locus of Control Scale CLCS (validated by Cousson-Gélie et al., 2005) 5. Social support is measured using the Social Support Questionnaire SSQ (validated by Segrestan, Rascle, Cousson-Gélie, & Trouette, 2007). All secondary data is collected at baseline, 2 months, 4 months and 6 months.

Countries

France

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026