Medical abortion Pregnancy and Childbirth Abortion
Conditions
Interventions
Patients will be randomised into two groups:
1. Group one will be treated using misoprostol with three drops of water (the 'water group')
2. Group two will only use misoprostol (the 'no water group')
Sponsors
Hong Kong Health Services Research Fund (Hong Kong)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. The duration of menstrual delay is less than 49 days 2. The size of the uterus on pelvic examination is compatible with the estimated duration of pregnancy 3. A positive pregnancy test 4. There is no history of significant medical illness 5. Age greater than 16 years old 6. Requests legal termination of pregnancy
Exclusion criteria
Exclusion criteria: 1. History or evidence of disorders that represent a contraindication to the use of misoprostol (mitral stenosis, glaucoma, sickle cell anaemia, diastolic pressure >100 mm Hg, bronchial asthma) 2. History or evidence of thrombo-embolism, severe or recurrent liver disease or pruritus of pregnancy 3. Presence of intrauterine contraceptive device (IUCD) in utero 4. Suspect or proven ectopic pregnancy 5. Heavy smoker (smoking >10 cigarettes daily in the past 2 years) or had another risk factor for cardiovascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
Hong Kong
Outcome results
None listed