Study of the relationship between asthma, asthma medications and performance

Association of asthma, lung function and medication use with performance among elite athletes: A prospective cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN18009118

Enrollment

200

Registered

2025-01-02

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma Respiratory

Interventions

In addition to a planned physiological test, athletes will be invited to: Complete two questionnaires (Allergy Questionnaire for Athletes, AQUA, and a subset of questions from the ECHRS III questionna

Eligibility

Sex/Gender

All

Age

16 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Swedish elite senior (age 21+ years) and junior (age 16-20) athletes 2. Active in cross-country skiing, biathlon, alpine skiing or other relevant disciplines 3. With a planned physiological test at the Swedish Winter Sports Research Centre's test lab 4. Where VO2max is to be determined through a running, roller-skiing or cycling test

Exclusion criteria

Exclusion criteria: Incomplete tests or data (such as an aborted test) - usually a posteriori

Design outcomes

Primary

Measure	Time frame
VO2max measured using dynamic spirometry in laboratory testing before and after exercise	—

Secondary

Measure	Time frame
The following secondary outcome measures are assessed during submaximal and maximal exercise testing: 1. Physiological and performance-related measurements are as follows: 1.1. Oxygen uptake, ventilation, expired O2 and CO2, tidal volume, and breathing frequency, measured using ergospirometry 1.2. Heart rate measured using electrocardiography 1.3. Cadence measured using manual counting or accelerometer/ergometer detection 1.4. Breathing patterns determined using linear and nonlinear analysis of ergospirometry variables 1.5. Treadmill speeds at submaximal and maximal workloads, measured using internal ergometer sensors 1.6. Test durations measured using a stopwatch 1.7. Blood lactate concentrations measured in the laboratory using a standard fingerprick blood test (Biosen S-Line, EKF diagnostics, Cardiff, UK) 2. Workload at given physiological thresholds measured in Watts 3. Perceived exertion measured using a Borg 6-20 RPE scale and perceived dyspnea using a Borg CR10 scale. 4. Ventilatory function (FEV1, FVC, PEF, FEV6, FEF25-75) measured using dynamic spirometry	—

Measure

Time frame

The following secondary outcome measures are assessed during submaximal and maximal exercise testing: 1. Physiological and performance-related measurements are as follows: 1.1. Oxygen uptake, ventilation, expired O2 and CO2, tidal volume, and breathing frequency, measured using ergospirometry 1.2. Heart rate measured using electrocardiography 1.3. Cadence measured using manual counting or accelerometer/ergometer detection 1.4. Breathing patterns determined using linear and nonlinear analysis of ergospirometry variables 1.5. Treadmill speeds at submaximal and maximal workloads, measured using internal ergometer sensors 1.6. Test durations measured using a stopwatch 1.7. Blood lactate concentrations measured in the laboratory using a standard fingerprick blood test (Biosen S-Line, EKF diagnostics, Cardiff, UK) 2. Workload at given physiological thresholds measured in Watts 3. Perceived exertion measured using a Borg 6-20 RPE scale and perceived dyspnea using a Borg CR10 scale. 4. Ventilatory function (FEV1, FVC, PEF, FEV6, FEF25-75) measured using dynamic spirometry

—

Countries

Sweden

Contacts

Public ContactHelen Hanstock

helen.hanstock@miun.se+46 0101428124

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 7, 2026