Clinical trial comparing surgical and conservative treatment in patients with anterior temporomandibular disc displacement without reduction

A prospective controlled clinical trial comparing surgical and conservative treatment in patients with irreducible anterior displacement of the temporomandibular joint disc

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN18007970

Enrollment

200

Registered

2023-02-07

Start date

2023-02-10

Completion date

Unknown

Last updated

2023-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint anterior disc displacement without reduction Oral Health

Interventions

This study is a prospective, randomized clinical trial study designed to systematically explore the effect of surgical and conservative treatment on the recovery of temporomandibular joint function. T

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with temporomandibular joint anterior disc displacement without reduction (ADDWoR) 2. Aged 18-45 years old 3. Willing to participate in the clinical study and sign informed consent of meeting the above-mentioned criteria

Exclusion criteria

Exclusion criteria: 1. Previous treatment for temporomandibular joint disorders 2. Infection, tumor, trauma, and other diseases 3. Jaw deformity, dentition defect, inability to form stable occlusion, and severe occlusion disorder 4. The disc is seriously deformed and perforated, and the operation of the articular disc cannot be performed 5. Immune system disease suffering from rheumatoid arthritis

Design outcomes

Primary

Measure	Time frame
1. Examination of mandibular movement (mouth opening degree, mouth opening type, forward extension, and lateral movement) performed by an inspection measured using a measurement of mouth opening scale at 3 and 6 months 2. Joint murmur, including bounce and friction sound, measured using auscultation at 3 and 6 months 3. Joint area tenderness of the lateral joint capsule, posterior condyle area, condyle going backwards through the external auditory canal measured using palpation at 6 and 12 months 4. Masticatory tenderness (temporal muscle, digastric muscle, medial pterygoid, sternocleidomastoid, and trapezius) measured using palpation at 3 and 6 months 5. Resting and occlusal pain measured using a Visual Analogue Scale (VAS) at 6 and 12 months 6. Morphological analysis of articular disc and analysis of reconstruction of the temporomandibular joint disc measured using MRI examination 6, 12, and 24 months 7. Morphological analysis of temporomandibular joint condyle, and analysis of condylar reconstruction measured using small-field cone beam computed tomography (CBCT) examination at 6, 12, and 24 months	—

Measure

Time frame

1. Examination of mandibular movement (mouth opening degree, mouth opening type, forward extension, and lateral movement) performed by an inspection measured using a measurement of mouth opening scale at 3 and 6 months 2. Joint murmur, including bounce and friction sound, measured using auscultation at 3 and 6 months 3. Joint area tenderness of the lateral joint capsule, posterior condyle area, condyle going backwards through the external auditory canal measured using palpation at 6 and 12 months 4. Masticatory tenderness (temporal muscle, digastric muscle, medial pterygoid, sternocleidomastoid, and trapezius) measured using palpation at 3 and 6 months 5. Resting and occlusal pain measured using a Visual Analogue Scale (VAS) at 6 and 12 months 6. Morphological analysis of articular disc and analysis of reconstruction of the temporomandibular joint disc measured using MRI examination 6, 12, and 24 months 7. Morphological analysis of temporomandibular joint condyle, and analysis of condylar reconstruction measured using small-field cone beam computed tomography (CBCT) examination at 6, 12, and 24 months

—

Secondary

Measure	Time frame
Psychological evaluation of the quality of life measured using the OHI oral health Index at 6 and 12 months	—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026