Effect of the order of lung tumor removal and lymph node dissection on circulating tumor cells during lung cancer surgery

A prospective observational study evaluating the influence of surgical sequence (lung-first versus lymph node-first) on perioperative circulating tumor cell dynamics in patients undergoing surgical resection for non-small cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN17981262

Enrollment

Registered

2026-03-10

Start date

2023-05-01

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resectable non-small cell lung cancer (NSCLC) Cancer

Interventions

This was a prospective, non-randomized, two-arm observational study including 60 patients with resectable non-small cell lung cancer undergoing surgical resection (May–December 2023). Participants wer

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 80 years 2. Newly diagnosed primary lung malignancy confirmed as NSCLC by pathology or cytology 3. No previous malignant tumor in other organs 4. No distant metastasis on preoperative imaging 5. Adequate cardiac, hepatic, pulmonary and renal function 6. Written informed consent provided

Exclusion criteria

Exclusion criteria: 1. Age 80 years 2. Non-NSCLC lung tumors 3. Severe organ dysfunction or surgical contraindications 4. Autoimmune diseases or coagulation disorders 5. Previous malignant tumors 6. Refusal to participate or inability to provide informed consent

Countries

China

Contacts

Public ContactZou Guowen

guowenzou1988@163.com+86 (0)18070495050

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 3, 2026