Bacterial infection in ventilated preterm neonates Infections and Infestations Bacterial infection in ventilated preterm neonates
Conditions
Interventions
As part of routine care, ventilator tubes are cleared of mucus which can build up over time. It is this waste material, which we will use to assess the feasibility of the new device to detect Ureaplas
Sponsors
Cardiff Metropolitan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Babies born between 25 and 30 weeks gestational age
Exclusion criteria
Exclusion criteria: 1. Parents of any baby which are deemed not to have the capacity to consent 2. Parents of any baby who cannot speak English or Welsh 3. Baby receiving palliative care 4. Parents are under the age of 16 years 5. Baby under a care order 6. Any other reason that the clinical lead feels it may be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Sensitivity of the new diagnostic device - estimates of the new diagnostic device positive rate in comparison with qPCR methods currently used. 2. Specificity of the new diagnostic device - estimates of the new diagnostic device negative rate in comparison with qPCR methods currently used. 3. Estimate of the positive predictive and negative predictive value of the new diagnostic device as other basic measures of diagnostic accuracy given their relationship to sensitivity and specificity through disease prevalence . | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between qPCR copy numbers and the new diagnostic device values obtained using regression analysis | — |
Countries
United Kingdom, Wales
Contacts
Public ContactMichael Beeton
Outcome results
None listed