How girls' and boys' glucose and insulin responses to high and low glycaemic index meals are different during puberty

Sex differences in adolescents’ glycaemic and insulinaemic responses to high and low glycaemic index breakfasts

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17903058

Enrollment

Registered

2016-09-21

Start date

2009-10-01

Completion date

Unknown

Last updated

2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glycaemic and insulinaemic responses Nutritional, Metabolic, Endocrine Glycaemic and insulinaemic responses

Interventions

Participants are individually, randomly allocated to a trial order using the ‘ABBA’ method. Participants then consumed two breakfasts in the order based upon the allocation process on two separate day

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 11-14 years 2. Healthy;Inclusion criteria: 1. Aged 11-14 years 2. Healthy

Exclusion criteria

Exclusion criteria: 1. Any condition which may make the taking of capillary blood samples problematic 2. Any food allergies or intolerances to the foods provided;Exclusion criteria: 1. Any condition which may make the taking of capillary blood samples problematic 2. Any food allergies or intolerances to the foods provided

Design outcomes

Primary

Measure	Time frame
1. Blood glucose concentration is measured using the GOD-PAP method using capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition 2. Plasma insulin concentration is measured using an ELISA assay on capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition;1. Blood glucose concentration is measured using the GOD-PAP method using capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition 2. Plasma insulin concentration is measured using an ELISA assay on capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition	—

Measure

Time frame

1. Blood glucose concentration is measured using the GOD-PAP method using capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition 2. Plasma insulin concentration is measured using an ELISA assay on capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition;1. Blood glucose concentration is measured using the GOD-PAP method using capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition 2. Plasma insulin concentration is measured using an ELISA assay on capillary blood samples at baseline and 15, 30, 60 and 120 minutes following the breakfast in each trial condition

—

Secondary

Measure	Time frame
Insulin resistance is measured using HOMA (Homeostatic Model Assessment), calculated using the fasting blood glucose and plasma insulin concentrations collected at baseline.;Insulin resistance is measured using HOMA (Homeostatic Model Assessment), calculated using the fasting blood glucose and plasma insulin concentrations collected at baseline.	—

Countries

United Kingdom

Contacts

Public Contact; ;

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Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026