The use of misoprostol suppositories to reduce radiotherapy-induced anorectal dysfunction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17865479

Enrollment

Registered

2003-09-12

Start date

2002-07-01

Completion date

Unknown

Last updated

2017-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute radiation proctitis Digestive System Other diseases of anus and rectum

Interventions

Randomised controlled clinical trial: 1. Misoprostol suppositories 2. Placebo

Eligibility

Inclusion criteria

Inclusion criteria: 50 patients from oncology

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
A reduction in acute radiation proctitis symptoms.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026