Combined arm cycling and standard exercise training for improving trunk function after spinal cord injury

Functional activity of upper extremities to improve trunk function after spinal cord injury

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17864031

Enrollment

Registered

2020-10-29

Start date

2021-07-01

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable, lower cervical or upper thoracic, incomplete spinal cord injury Injury, Occupational Diseases, Poisoning

Interventions

Participants will be randomized into one of the two groups: the experimental group and the control group using minimisation methods ensuring balance in prognostic factors (e.g. level of injury, years

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: SCI participants will be included if they have: 1. A stable, lower cervical or upper thoracic, incomplete spinal cord injury. 2. Ability to voluntarily move the elbow to operate the arm bike. 3. Visible motor evoked potentials (MEPs) in erector spinae (ES) muscles induced by transcranial magnetic stimulation (TMS). This is to ensure changes in corticospinal function are measurable

Exclusion criteria

Exclusion criteria: Participants will be excluded if they meet the criteria for exclusion for the use of TMS (Rossi et al., 2011): 1. Metal implants, cardiac pacemaker, history of epilepsy or fits, previous brain injury, neurosurgery of the brain, neurological disorders other than spinal cord injury, psychological disorders, actively taking antidepressant or other neuromodulatory drugs 2. Participants are pregnant or breastfeeding 3. Participants are under the age of 18

Design outcomes

Primary

Measure	Time frame
Dynamic sitting balance assessed by multidirectional reach test at baseline, 4, 8 and 16 weeks	—

Secondary

Measure	Time frame
1. Neuromuscular and corticospinal function of the trunk muscles measured using non-invasive transcranial magnetic stimulation at baseline, 4, 8 and 16 weeks 2. Mobility measured using time of 3-meter walking or wheelchair transfer at baseline, 4, 8 and 16 weeks 3. Pressure relief measured using a force plate at baseline, 4, 8 and 16 weeks 4. Trunk control measured using trunk impairment scale at baseline, 4, 8 and 16 weeks 5. Function of upper extremities measured using a dynamometer and the Action Research Arm Test at baseline, 4, 8 and 16 weeks	—

Measure

Time frame

1. Neuromuscular and corticospinal function of the trunk muscles measured using non-invasive transcranial magnetic stimulation at baseline, 4, 8 and 16 weeks 2. Mobility measured using time of 3-meter walking or wheelchair transfer at baseline, 4, 8 and 16 weeks 3. Pressure relief measured using a force plate at baseline, 4, 8 and 16 weeks 4. Trunk control measured using trunk impairment scale at baseline, 4, 8 and 16 weeks 5. Function of upper extremities measured using a dynamometer and the Action Research Arm Test at baseline, 4, 8 and 16 weeks

—

Countries

England, United Kingdom

Contacts

Public ContactShinyi Chiou

s.chiou@bham.ac.uk+44 (0)121 414 5315

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026