The effectiveness of aloe vera extract on socket healing after dental extraction

Evaluation of the effectiveness of aloe vera in soft tissue healing and socket preservation after extraction

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17779220

Enrollment

Registered

2022-04-22

Start date

2019-10-15

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue healing and socket preservation after dental extraction Oral Health

Interventions

After taking the patient's medical history and evaluating their general health according to the research conditions, written consent will be taken on the content and terms of the research, and researc

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who accepted participation with written consent 2. Adults aged 18-45 years 3. Patients need bilateral upper or lower premolars extraction

Exclusion criteria

Exclusion criteria: 1. Heavy smokers 2. Pregnant 3. Uncontrolled diabetes patients 4. Presence of cysts or tumors at the extraction site 5. Patients with advanced periodontitis 6. Patients who are allergic to the plants of the Liliaceae family

Design outcomes

Primary

Measure	Time frame
1. Pain measured using a visual analogue scale (VAS) 2 hours after extraction and on the third and seventh day 2. Healing assessed by the Landry et al. healing index on the third and seventh day 3. The dimensions of the alveolar bone assessed by cone-beam computed tomography (CBCT) immediately after extraction and after 4 months	—

Secondary

Measure	Time frame
The dimensions of the alveolar bone assessed by CBCT after 4 months	—

Countries

Syria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026