Pneumothorax Respiratory Pneumothorax
Conditions
Interventions
This study will collect data retrospectively for up to 450 patients (aged 16 to 50 years) seen in the Cambridge Pneumothorax Clinic. An equal number of controls, matched for age, sex, socio-economic s
Sponsors
Cambridge University Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 16-50 years seen in the Cambridge Pneumothorax Clinic 2. Matched individuals recruited from unrelated clinics at Cambridge University Hospitals (CUH) NHS Foundation Trust
Exclusion criteria
Exclusion criteria: Traumatic pneumothorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative risk of pneumothorax in cannabis smokers measured using unconditional logistic regression adjusted for possible confounders including the matching variables (age, sex and area of residence) and smoking habits at a single timepoint (cases: first attendance at pneumothorax; controls: at completion of the questionnaire in a non-pneumothorax clinic). The odds ratio and associated 95% confidence limits will be estimated. All analyses will be carried out in R using the glm command implemented in the stats package. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Cannabis and tobacco usage in the local population measured using a bespoke questionnaire at attendance at a non-pneumothorax clinic on a single occasion 2. The potential interaction between cannabis and tobacco smoking in pneumothorax evaluated by including an interaction term in the logistic regression model at first attendance at pneumothorax (cases) or at completion of the questionnaire in a non-pneumothorax clinic (controls) | — |
Countries
England, United Kingdom
Outcome results
None listed