Hypertension Circulatory System
Conditions
Interventions
Patients randomized to the intervention group will follow the medicine, exercise, sleep and nutritional syntax of the Twin Precision Treatment program.
Group 1 Standard care arm
Sponsors
Twin Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with a diagnosis of primary hypertension (either adequately controlled or inadequately controlled with blood pressure =180/110 mm Hg); both treatment-naive & on treatment (includes monotherapy or multiple drugs) 2. Aged 18 years and above 3. Willing to follow study specific activities and able to handle smartphone
Exclusion criteria
Exclusion criteria: 1. Uncontrolled hypertension (>180/110 mm of Hg) or history of hypertensive emergency requiring admission 2. Hypertension due to secondary causes 3. History of Diabetes mellitus (when either of the following criteria is met: on medications to control blood sugar or FBS >126 mg/dl; RBS >200 mg/dl; HbA1c =6.5) 4. Symptomatic heart failure or EF 10.5 mg/dl) and Hyperkalemia.(>5.5 mmol/l) 13. Known Malignant cases 2 mg/dL or aspartate aminotransferase (AST) and alanine aminotransferase (ALT) 5 times the upper limit of normal range 21. Pregnant or planning to conceive in the next 3 years or breastfeeding 22. Psychiatric illness such as psychosis, manic depressive illness, alcohol or drug dependence. 23. Consumption of >14 alcoholic beverages per week (for women) and >21 for men 24. Any other condition or illness that the investigator feels would make the patient ineligible or make the patient difficult to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Blood pressure as measured by ambulatory blood pressure monitoring at baseline and the end of 1 year 2. Blood pressure as measured in the clinic at baseline and the end of 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood pressure (clinical and ambulatory blood pressure) at baseline, 6 months, and 2 years 2. Adequate control of blood pressure as measured by ambulatory blood pressure monitoring at 1 year and 2 years Criteria for adequate control of blood pressure is: In <65 years < 130/80 mm Hg In 65 and above < 140/90 mm Hg 3. Number of antihypertensive medications at 6 months, 1 year and 2 years measured using patient records | — |
Countries
India
Outcome results
None listed