Unruptured intracranial aneurysms Circulatory System
Conditions
Interventions
A cohort of patients with unruptured intracranial aneurysms identified by searches of scan reports, clinic letters and multi-disciplinary team (MDT) outcomes at neurosurgical units in the United Kingd
Sponsors
University Hospital Southampton NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Intracranial intradural unruptured aneurysm, confirmed on angiogram (Computed Tomography Angiogram [CTA], Magnetic Resonance Angiography [MRA], Digital Subtraction Angiography [DSA]) 2. Diagnosis of Unruptured Intracranial Aneurysm [UIA] between January 2006-December 2020.
Exclusion criteria
Exclusion criteria: 1. Mycotic or vasculitic aneurysms 2. Aneurysm diagnosed on computed tomography (CT) or magnetic resonance imaging (MRI) alone 3. Arteriovenous malformation (AVM) associated flow aneurysms 4. Extradural aneurysms (e.g. intra-cavernous) 5. Aneurysms previously treated by either microsurgical or endovascular techniques 6. Small lesions uncertain as to whether they are truly aneurysmal (“dilatation”, “bulge”, ‘Infundibulum”)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rupture of a previously diagnosed unruptured intra-cranial aneurysm demonstrated on CT imaging or sections 1a-c on a death certificate after aneurysm diagnosis | — |
Secondary
| Measure | Time frame |
|---|---|
| Growth of an unruptured intracranial aneurysm demonstrated on angiographic imaging after diagnosis | — |
Countries
England, United Kingdom, Wales
Contacts
Public ContactDiederik Bulters
Outcome results
None listed