Early outcome of prenatally diagnosed Ventriculomegaly by general movement Assessment

Early neurological outcome of prenatally diagnosed ventriculomegaly at 20 weeks of gestation, using the qualitative assessment of general movements

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN17606645

Enrollment

Registered

2013-11-12

Start date

2013-10-01

Completion date

Unknown

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventriculomegaly Neonatal Diseases

Interventions

This is an observational study in which the short-term neurological outcome, etiology and survival in children with prenatally diagnosed hydrocephalus will be determined prospectively. Maternal, anten

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Newborn child 2. Aged less than one week 3. Having been diagnosed with ventriculomegaly (>10 mm ventricular width) as foetus

Exclusion criteria

Exclusion criteria: 1. Diagnosis of spina bifida 2. First ultrasound at more than 23 weeks of gestation

Design outcomes

Primary

Measure	Time frame
To determine whether the short-term neurological outcome of surviving children diagnosed with prenatally diagnosed ventriculomegaly is associated with the extent of VM before birth. The quality of fidgety general movements (FMs) and the motor optimality score (MOS) will be determined at 3 months (11-15 weeks) after term, from video recordings.	—

Secondary

Measure	Time frame
To determine whether the etiology of VM and presence of associated anomalies is associated with short-term neurological outcome of children with prenatally diagnosed VM. As secondary outcome measure the quality of GMs and the MOS will be assessed at 1 week after birth, and in preterm children (born before 36 weeks) also at term equivalent age (40 weeks ± 14 days post menstrual age), and in all children around 18 weeks (16-20 weeks) after term.	—

Measure

Time frame

To determine whether the etiology of VM and presence of associated anomalies is associated with short-term neurological outcome of children with prenatally diagnosed VM. As secondary outcome measure the quality of GMs and the MOS will be assessed at 1 week after birth, and in preterm children (born before 36 weeks) also at term equivalent age (40 weeks ± 14 days post menstrual age), and in all children around 18 weeks (16-20 weeks) after term.

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Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026