SARS-COV-2 Infections and Infestations
Conditions
Interventions
Standard of care (SOC) arm with professional-use rapid diagnostic tests (C19RDTs) for diagnostic testing of symptomatic HCWs.
Intervention arm with SOC plus twice-weekly COVID-19 Ag-RDT self-testing (
Sponsors
Unitaid
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Healthcare workers shall be eligible to participate if they are: 1. Aged 18 years and above 2. All health workers employed by the above facilities, including nurses, doctors, clinic assistants, health surveillance assistants, clinical officers, community health workers and lay counsellors, administrators and support staff such as receptionists and porters. 3. Willing and able to give written informed consent
Exclusion criteria
Exclusion criteria: A healthcare worker shall be ineligible to participate if they: 1. Have tested positive for COVID-19 and are still within the isolation period 2. Have any medical contraindication to anterior nasal swab (e.g. bleeding disorders, recent facial trauma)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Harmonic mean number of HCWs with confirmed COVID-19 measured through a count of number of HCWs with confirmed COVID-19 by PCR or rapid testing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured by self-report at one month follow-up face-to-face interview: 1. Health care workers reporting any illness in the last 28 days 2. Health care workers taking time off work in the last 28 days 3. Health care workers having cough and fever in the last 28 days | — |
Countries
Malawi
Outcome results
None listed