Root perforation Oral Health Root perforation
Conditions
Interventions
Participants are randomly assigned to one of two groups, either the MTA group of the Biodentine group. Two teeth that are scheduled for extraction are randomly assigned to either being designated the
Sponsors
Clinica Odontoiatrica Salzano Tirone
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults aged 18-60 years old 2. Healthy patients 3. Needing all-on-4 rehabilitation 4. Having at least two vital and periodontally healthy monoradicular teeth scheduled for extraction
Exclusion criteria
Exclusion criteria: 1. Clinically significant medical history 2. Treated with immunosuppressive therapy or immunocompromised 3. Undergoing radiotherapy in the head/neck area 4. Previously treated or under treatment with intravenous amino-bisphosphonates 5. Pregnant or breastfeeding 6. Refusing to be included in the research protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Formation of mineralised tissue over the filling material material is measured using the histological analysis at 3 months 2. PDL fibres orientation is evaluated using thehistological analysis under polarised light at 3 months 3. Presence of inflammatory cell infiltrate, classified as follows: null, when there are no inflammatory cells; mild, when there are few inflammatory cells; moderate, when inflammatory cells do not replace the normal tissue; severe, when inflammatory cells replace the normal tissue is measured using the histological analysis at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The presence or absence of a fibrous capsule formation is measured using histological analysis at 3 months 2. Root resorption is measured using histological analysis at 3 months 3. Ankylosis is measured using histological analysis at 3 months 4. Epithelial proliferation is measured using histological analysis at 3 months | — |
Countries
Italy
Contacts
Public ContactTirone Federico
Outcome results
None listed