Chronic endometritis Infections and Infestations
Conditions
Interventions
Chronic endometritis was diagnosed through hysteroscopy and immunohistochemistry for CD 138. Patients in both groups were tested for CE twice to evaluate the cure rate after oral combination antibioti
Sponsors
CALLA Infertility Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Undergoing an IVF procedure at the clinic following various IVF recommendations 2. Obtained at least two of day 5-6 blastocyst 3. Agreed to have hysteroscopic examination
Exclusion criteria
Exclusion criteria: 1. Acute endometritis or other acute pelvic inflammatory disease 2. Placental remnants 3. Steroidal and antibiotic treatment within 3 months prior to diagnosis 4. Endometrial cancer or atypical hyperplasia 5. Refusal of procedure (hysteroscopy), or treatment for chronic endometritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Prevalence of chronic endometritis (CE) in a population that undergoes an IVF procedure measured using immunohistochemistry staining for CD 138 positivity over 1 year 2. Rate of CE resolution in patients receiving oral versus an intrauterine infusion of antibiotics measured using immunohistochemistry staining for CD 138 negativity at the control biopsy over 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of the hysteroscopic aspect with the positive CD 138 immunohistochemical staining measured by the number of pathological hysteroscopies that also have positive CD 138 staining over 1 year | — |
Countries
Romania
Outcome results
None listed