Remineralization capacity of CPP-ACP Oral Health
Conditions
Interventions
Participants will be allocated equally into two groups: Group 1 (intervention) receive GC Tooth Mousse (CPP-ACP) and Group 2 (control) receive a placebo mousse.
A random allocation li
Sponsors
Damascus University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Good oral hygiene 2. Participants not be taking antibiotics or any kind of medications that can affect the flow rate of saliva 3. Does not suffer from an allergy to milk protein confirmed or suspected and/or the presence of the sensitivity of benzoate (preservative)
Exclusion criteria
Exclusion criteria: 1. Taking antibiotics or drugs that may affect the salivary flow rate 2. The existence of diseases that may affect the flow rate of saliva or a combination such as diabetes 3. Sensitivity to milk protein confirmed or suspected and/or the presence of the sensitivity of benzoate (preservative)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured at T0: before the application (baseline); T1: directly after the application ; T2: after half an hour; T3: after 1 hour: 1. pH of saliva measured using pH test strips (Whatman® Panpeha™ pH indicator strips) 2. Salivary flow rate measured by calculating the amount of saliva which will be collected in tubes and dividing it into five to see the amount of saliva secreted per minute (ml/d) | — |
Secondary
| Measure | Time frame |
|---|---|
| Calcium concentration of saliva measured using Calein as an indicator, ethylenediaminetetra-acetate (EDTA) as a Ca-complexing agent, and a standard Ca solution to set up the calibration series; measured at T0: before the application (baseline); T1: directly after the application ; T2: after half an hour; T3: after 1 hour. | — |
Countries
Syria
Outcome results
None listed