Ischemic stroke or transient ischemic attack Circulatory System Cerebral infarction, unspecified
Conditions
Interventions
A 6-month exercise program with either continuous exercise or a combination of high-intensity training combined with continuous exercise training.
The 1-year follow-up randomized cont
Sponsors
Université du Québec à Trois-Rivières
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ischemic stroke or TIA with a minimum of 3 months post event and no maximum 2. Age 40 years and over 3. Ambulatory capacity over 10 min with or without assistive devices as needed 4. Not currently participating in formal rehabilitation
Exclusion criteria
Exclusion criteria: 1. TIA with either isolated sensory symptoms, visual changes or vertigo 2. Presence of brain hemorrhage, vascular malformations, tumor, abscess or other major non-ischemic cerebral disease 3. Cognitive impairment limiting task comprehension 4. Any musculoskeletal troubles that prevent physical activity practice 5. Lower extremity claudication 6. All absolute contraindications to exercise testing according to the American College of Sports Medicine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiorespiratory fitness measured with peak oxygen uptake (VO2 peak) at the university hospital. The GTX protocol was performed on a semi-recumbent ergocycle with 12-lead ECG monitoring (MAC 5500HD, GE Healthcare, USA). The cadence was maintained at 60 rpm; power started between 0 watts and 60 watts depending on the participant’s capacity and increased progressively by 10 watts per minute. These tests were performed at baseline (T0) after the 6-month intervention (T6), and after 12 months (T12) at the university or hospital. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured at baseline (T0) after the 6-month intervention (T6), and after 12 months (T12): 1. Resting systolic and diastolic blood pressure measured twice on each arm with the participant in a sitting position. The result was the average of the two measures taken with an automated sphygmomanometer (HEM-907XL, Omron IntelliSense, USA) in accordance with the recommendations of the Canadian Education Hypertension Program. The resting heart rate was simultaneously recorded and the average was reported. 2. Low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides, total cholesterol and HbA1c analyzed with standardized procedures at the Centre Hospitalier Universitaire régional de Trois-Rivières, Québec, Canada 3. Waist circumference measured in a standing and relaxed position using a flexible measuring tape 4. Body weight and height measured with a stadiometer (402LB, Health-o-meter, USA) and used to calculate body mass index (BMI) 5. Body fat mass calculated with bioelectrical impedance (BC-418, TANITA, USA) 6. Self-reported physical activity recorded with the Godin Leisure-Time Exercise Questionnaire (GLTEQ) 7. Functionality and frailty assessed with the Short Physical Performance Battery (SPPB) 8. Psychological distress assessed with the Hospital Anxiety and Depression Scale (HAD) 9. Cognitive function assessed with the Montreal Cognitive Assessment (MoCA) 10. Acceptability of the intervention assessed with a French version of the Treatment Acceptability and Preferences Questionnaire (TAPQ) at the 12-month evaluation by an independent evaluator | — |
Countries
Canada
Outcome results
None listed