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Malignant transformation and tumour recurrence in sacrococcygeal teratoma, a congenital disorder in newborns

Malignant transformation and tumour recurrence in patients with SacroCoccygeal Teratoma: a global, retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN17493302
Enrollment
1000
Registered
2024-04-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sacrococcygeal teratoma Cancer

Interventions

This observational study looks at tumour histology at initial resection and the time between birth and surgery. Furthermore, risk factors associated with recurrence will be analysed. Collected data

Sponsors

Foundation KiKa
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with SCT treated by each participating centre during a set time

Exclusion criteria

Exclusion criteria: Patients treated for sacrococcygeal teratoma before 1980

Design outcomes

Primary

MeasureTime frame
The following primary outcomes are measured using patient medical records at a one-time point: 1. Malignant transformation of the initial tumour confirmed by pathology. 2. Risk factors associated with sacrococcygeal teratoma recurrence defined as relapse of the tumour at least three months after initial resection.

Secondary

MeasureTime frame
The following secondary outcomes are measured using patient medical records at a one-time point: 1. Treatment modality for sacrococcygeal teratoma patients from different income countries 2. Outcomes of treatment for sacrococcygeal teratoma patients from different income countries

Countries

Afghanistan, Argentina, Austria, Bangladesh, Belarus, Belgium, Brazil, Bulgaria, Cameroon, Canada, Chile, China, Côte d'Ivoire, Croatia, Czech Republic, Denmark, Egypt, Estonia, Ethiopia, Finland, France, Germany, Ghana, Greece, Hong Kong, Hungary, India, Indonesia, Iran, Iraq, Ireland, Israel, Italy, Japan, Korea, South, Latvia, Lithuania, Malaysia, Mexico, Montenegro, Morocco, Netherlands, Nigeria, North Macedonia, Norway, Pakistan, Philippines, Poland, Portugal, Romania, Russian Federation, Serbia, Singapore, Slovakia, Slovenia, Spain, Sri Lanka, Sweden, Syria, Taiwan, Thailand, Tunisia, Türkiye, Ukraine, United Kingdom, United States of America, Zambia

Contacts

Public ContactLieke van Heurn
l.j.vanheurn@amsterdamumc.nl+31 20 566 5693

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026