The effect of low pressure pneumoperitoneum and pulmonary recruitment maneuver on postoperative pain after laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17470334

Enrollment

Registered

2017-11-08

Start date

2015-05-26

Completion date

Unknown

Last updated

2017-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Optimalisation of pain relief after laparoscopic cholecystectomy Surgery Laparoscopic cholecystectomy

Interventions

Low pressure pneumoperitoneum in all patiënts Pulmonary recruitment maneuver at the end of the surgery in 1 of the 2 groups Participants are randomly allocated to one of two groups: Group 1: Control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients for elective laparoscopic surgery for gall stone disease 2. ASA I and II 3. More than 18 years old

Exclusion criteria

Exclusion criteria: 1. Refusal to give consent 2. Cholecystitis 3. BMI above 35 4. Intolerance to one of the pain medication 5. Pregnancy

Design outcomes

Primary

Measure	Time frame
Pain relief during the first 24 hours is measured using the VAS (visual analogue scale) at fixed time point: 0-1-6-12-18-24 hours postoperatively.	—

Secondary

Measure	Time frame
1. Total analgesic use during the first 24 hours is measured: the amount of using/needing painkilling during hospitalisation (difference in need of morphine sulphate and tramadol IV (in milligram)) 2. Recovery after 48 hours is measured using the postoperative 15-item patient-rated quality of recovery questionnaire by telephone call 3. Nausea and vomiting is measured using patient personal experience 4. Length of hospital stay is measured using time in hours 5. Requirement for increased pressure during surgery is measured using: the place in the abdomen that is required to operated	—

Measure

Time frame

1. Total analgesic use during the first 24 hours is measured: the amount of using/needing painkilling during hospitalisation (difference in need of morphine sulphate and tramadol IV (in milligram)) 2. Recovery after 48 hours is measured using the postoperative 15-item patient-rated quality of recovery questionnaire by telephone call 3. Nausea and vomiting is measured using patient personal experience 4. Length of hospital stay is measured using time in hours 5. Requirement for increased pressure during surgery is measured using: the place in the abdomen that is required to operated

—

Countries

Belgium

Contacts

Public ContactIsabelle Casier

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026