Systemic therapy with prenatal mothers presenting with anxiety and/or depression

Systemic therapy with prenatal mothers presenting with anxiety and/or depression: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17416582

Enrollment

Registered

2023-09-20

Start date

2022-03-01

Completion date

Unknown

Last updated

2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antenatal anxiety and/or depression Mental and Behavioural Disorders

Interventions

Current interventions as of 01/05/2024: Mothers who during the prenatal period score above the cutoff point on the Edinburgh Postnatal Scale (EPDS)_ (13 or higher) and or the Generalised Anxiety Dis

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Expecting a baby and not exceeding 20 weeks of pregnancy to be able to receive the intervention (over a 19-week period) and be post-tested before giving birth 2. Scoring above the cut-off point on GAD and EPDS 3. Accepting to take part in the study

Exclusion criteria

Exclusion criteria: 1. Lone parents meaning mothers 2. Mothers with psychotic disorders and mood disorder with psychotic features 3. Suicidal behaviour disorder 4. Substance use disorder 5. Alcohol use disorder 6. Post-traumatic stress disorder 7. Anti-social personality disorder 8. Borderline personality disorder Criteria 2 -8 were identified through the use of the MINI

Design outcomes

Primary

Measure	Time frame
Level of anxiety and/or depression measured using EPDS, GAD-7 immediately after the end of the intervention	—

Secondary

Measure	Time frame
Distress in couple relationship measured using the Revised Dyadic Adjustment Scale (RDAS) post-intervention period	—

Countries

Malta

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026