Topic: Cardiovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years 2. Undergoing elective cardiac surgery (coronary artery bypass grafting, valve surgery or both) 3. One or more patient related risk factor for postoperative pulmonary complications (COPD, asthma, lower respiratory tract infection in last 4 weeks, body mass index=35 kg/m2 current (last 6 weeks) heavy smokers (> 10 pack years)) 4. Capable of performing a 6MWT. The 6MWT is a clinical exercise test, and is popular in clinical practice because it aids clinical decision making, and because of the belief that it provides a better estimate of functional capacity than resting cardiorespiratory measurements. The 6MWT is the most popular clinical exercise test, which is used for postoperative evaluation after lung surgery and has also been validated in cardiac surgery
Exclusion criteria
Exclusion criteria: 1. Contraindication to high flow nasal oxygen such as nasal septal defect 2. Not met extubation criteria by 10am the day after surgery (Day 1) 3. Need for CPAP preoperatively
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospital length of stay (days) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Early postoperative functional recovery, determined by 6 minute walk test (6MWT) 2. Early postoperative lung function, tested by spirometry 3. Intensive care unit (ICU) length of stay (days) 4. Requirement for escalation of respiratory support and ICU re-admission | — |
Countries
United Kingdom