A study of the biological availability of protein-derived ingredients

Investigating the metabolic end products of casein-derived bioactive peptides

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN17379716

Enrollment

Registered

2015-04-13

Start date

2015-01-01

Completion date

Unknown

Last updated

2015-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects Not Applicable

Interventions

Participants will be randomised to receive the three test drinks (labelled caseins containing bioactive peptides, labelled caseins that have not been broken down, or unlabelled caseins) in random orde

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy male and females free-living Caucasians aged 18-65 years

Exclusion criteria

Exclusion criteria: 1. A body mass index (BMI) 31.0 (kg/m2), 2. Any chronic or infectious disease 3. Any prescribed medication (contraceptive pills and hormone replacement therapy will be permitted) 4. Pregnant or lactating females

Design outcomes

Primary

Measure	Time frame
Appearance of casein-derived metabolites and fragments thereof in the plasma postprandially. Study subjects will attend the intervention suites in our research centre. At time 0, 10, 15, 30, 60, 90, 120, 180 and 240 minutes blood samples will be collected. Analysis will be performed at all timepoints.	—

Secondary

Measure	Time frame
Postprandial dietary nitrogen metabolism and hormonal profiles.	—

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026