Musculoskeletal health and function Musculoskeletal Diseases Musculoskeletal health and function
Conditions
Interventions
Participants are randomised to one of two group:
Exercise group (EX): Participants participate in a 20-week program combining sprint training (2 times/wk) with heavy and explosive str
Sponsors
University of Jyväskylä
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Voluntary men aged = 40 with long-term training background and success in international or national masters sprint events 2. Ongoing systematic training and competing 3. No diseases or musculoskeletal disorders contraindicating exercise or limiting participation in the training program
Exclusion criteria
Exclusion criteria: 1. Medical condition contraindicating intensive training 2. Use of medication affecting bone 3. Unwillingness to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone structure and strength are measured by peripheral quantitative computed tomography (pQCT) at baseline, after 20 weeks training period and at the 10 year follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Bone mineral content and volumetric density are measured by pQCT at baseline, after 20 weeks training period and at the 10 year follow-up 2. Anthropometry and body composition are measured by bioimpedance device at baseline, after 20 weeks training period and at the 10 year follow-up 3. Whole-muscle structural characteristics (quadriceps, triceps surae) is measured by pQCT and ultrasound at baseline, after 20 weeks training period and at the 10 year follow-up 4. Muscle needle samples were obtained from the middle region of the vastus lateralis muscle under local anaesthesia. Muscle fiber type, structure and single fiber contractile properties are measured by ATPase histochemistry, immunohistochemistry and skinned fiber experimental apparatus at baseline, after 20 weeks training period and at the 10 year follow-up 5. Blood and serum samples were taken for genetic, hormone, cytokine, growth factor analyses at baseline, after 10 and 20 weeks of training and at the 10 year follow-up. Automated immunoassay systems or commercial ELISA kits are used for the analyses 6. Muscle strength and power of leg and knee extensors and knee flexors (including explosive strength capability assessed by squat jump, triple jump with a standing start and a reactive hopping test) are measured by David 200 dynamometer, Smith machine and custom made dynamometry, force plate and contact mat at baseline, after 20 weeks training period and at the 10 year follow-up 7. Sprint running performance (30- and 60-meter) is measured on an indoor track equipped with a 9.4-m-long force platform by using double-beam photo-cell gates at baseline, after 20 weeks training period and at the 10 year follow-up. 8. Nutrient intake is obtained from 5-day food diaries kept in week 15 of the 20 weeks’ training period. 9. Bone mineral content, areal bone mineral density, lean body mass and | — |
Countries
Finland
Outcome results
None listed